Covalent drugs have emerged as a groundbreaking modality for improving the affinity, potency, and duration of action of molecularly targeted inhibitors. Prof. ... Read more

An innovative drainage device that addresses the unmet need for effective lymphedema and extremity edema treatments. The device features an implantable inert porous unit connected to a subcutaneous drainage tube leading to an external suction unit. ... Read more

A major challenge in developing viral-based therapies, such as gene therapies, CAR-T cell immunotherapy, and oncolytic virotherapy, is that the most efficient vectors and viruses are not specific, preventing their direct administration to the patient. Prof. ... Read more

Serum albumins are essential in a wide variety of molecular and cellular applications, including in the medical, biotechnological and cultivated meat industries. ... Read more

Enveloped viruses pose significant health risks and lack effective treatments. Inhibiting viral membrane fusion, a crucial step in infection, holds promise for antiviral drug development. Dr. ... Read more

Ovarian cancer is the fifth leading cause of cancer-related death in women. Due to a lack of early detection methods, it is often diagnosed at a late stage, resulting in negligible changes to cure. ... Read more

Psychiatric disorders, especially major depressive disorder (MDD), are leading causes of disability and premature death across the globe, with patients showing a heightened risk of self-harm and suicidal ideation. Prof. ... Read more

Prof. Elinav and his team have developed a novel approach to prevent weight gain by better understanding smoking cessation-associated weight gain (SCWG). ... Read more

Ewing sarcoma (ES) is a common bone malignancy in children and young adolescents which is usually treated by systemic chemotherapy. In about 25% of the cases, cancer has already spread to other parts of the body at the time of diagnosis. ... Read more

Immunotherapy has revolutionized cancer treatment by activating the immune system to attack tumor cells. However, notable limitations remain, including differential responses between individuals and cancer types. Dr. ... Read more