Therapeutics(25)
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Magnetic resonance imaging (MRI) Of Tissue Fibrosis without Contrast Agent (No. T4-1665)
Cardiac fibrosis is a scarring event in the cardiac muscle that causes abnormalities in cardiac function and significantly increases the risk of sudden cardiac death. ... Read more5575 -
Optimized MAGE-A1 targeting TCR for T-cell Therapy (No. T4-1662)
TCR gene therapies show promise in cancer treatment but are hindered by the low natural avidity of TCRs against tumor-associated antigens. MAGE-A1 is a germline antigen expressed in many tumor types, making it a compelling target for TCR-based immunotherapy. ... Read more5572 -
Repurposing Enoxacin: A Novel Therapeutic Strategy Targeting miRNA Biogenesis in ALS (No. T4-1632)
Amyotrophic Lateral Sclerosis (ALS) remains an incurable neurodegenerative disease, in need of innovative treatment options. Prof. Eran Hornstein and his team identified microRNAs (miRNA) as pivotal regulators of ALS progression. ... Read more18887 -
Targeted Inhibition of ADAM17 for the Treatment of Inflammatory Diseases and Cancer (No. T4-1628)
ADAM17 is a metalloprotease that regulates shedding of membrane-bound proteins, including IL-6, TNF-α, and others. ADAM17 is implicated in inflammatory diseases, fibrosis, cancer, and autoimmune conditions, making it a compelling target. ... Read more5551 -
Blood Test to Identify People at High Risk for Lung Cancer (No. T4-1033)
A novel diagnostic test to identify individuals with increased risk of lung cancer ... Read more5428
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