258 - Monoclonal antibody to Ermin
Description: Monoclonal antibody to Ermin (MAb160) raised against purified GSTErmin (residues 1261). Ermin is a marker of myelinating oligodendroglia, localized to the outer cytoplasmic lip of the myelin sheath and the paranodal loops. It was suggested to play a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis.
Reference: Brockschnieder D, Sabanay H, Riethmacher D, Peles E. 2006. Ermin, a myelinating oligodendrocyte-specific protein that regulates cell morphology. J Neurosci. 26(3):757-62.
Tech # 1269