You are here

Technology Number: 

288

Principal Investigator

Prof.
Benjamin
Geiger

Department: 

Molecular Cell Biology
Summary 

hVin monoclonal antibody

Description: Monoclonal antibodies raised against human Vinculin purified from human uterus. Specifically stains Vinculin at cell-cell and cell-substrate contacts in tissue and cultured cells. Good reactivity is obtained with human, bovine, chicken, dog, rat mouse, turkey and xenopus Vinculin.

Vinculin is a cytoskeletal protein associated with the cytoplasmic faces of both cell-cell and cell-extracellular matrix adherens-type junctions. It functions as one of

several interacting proteins involved in anchoring F-actin to the membrane.

Reference: Geiger B, Volk T, Volberg T, Bendori R. 1987. Molecular interactions in adherens-type contacts. J Cell Sci Suppl.8:251-72.

Applications


More technologies in Research Tools