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Scientist
101
Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry. Leukotrienes: §  101 – Monoclonal antibody to LTC4 Description: Rat monoclonal antibodies raised...

Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs

May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry.

Leukotrienes:

§  101 – Monoclonal antibody to LTC4

Description: Rat monoclonal antibodies raised against Leukotriene C4-KLH.

Available clone:  6E7 (IgG1).

Cysteinyl leukotrienes are potent lipid mediators in inflammation, inducing

smooth muscle contractions and increased capillary permeability.

 
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  • Dr. Fortune Kohen
103
103 - Bone marrow derived stroma cell line 14F1.1 Description: An endothelial-adipose cell line derived from a murine bone marrow stroma. Reference: Zipori D, Toledo J, von der Mark K. 1985. Phenotypic heterogeneity among stromal cell lines from mouse bone marrow disclosed in their extracellular...

103 - Bone marrow derived stroma cell line 14F1.1

Description: An endothelial-adipose cell line derived from a murine bone marrow stroma.

Reference: Zipori D, Toledo J, von der Mark K. 1985. Phenotypic heterogeneity among stromal cell lines from mouse bone marrow disclosed in their extracellular matrix composition and interactions with normal and leukemic cells. Blood. Aug;66(2):447-55.

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  • Prof. Dov Zipori
115
  Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry. Leukotrienes:   Veterinary drugs: § 115 - Monoclonal antibody to Sulfamethazine (SMZ)...

 

Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs

May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry.

Leukotrienes:

 

Veterinary drugs:

§ 115 - Monoclonal antibody to Sulfamethazine (SMZ)

Description: Rat monoclonal antibodies raised against Sulfamethazine-BSA.

    Available clone: 21C7, IgG1.

Sulfamethazine is an antibacterial agents commonly given to food animals (swine, fishetc.) to prevent disease and maximize production.

Reference: Fortune Kohen , Batya Gayer , Yehudith Amir-Zaltsman &

Michael O'Keeffe. 2000. Generation of an anti-idiotypic antibody as a surrogateLigand for sulfamethazine in immunoassay procedures, food and agricultural. Immunology 12:3 193-201.

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  • Dr. Fortune Kohen
116
Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry.   Biotin: §  116, 142 – Monoclonal antibody to Biotin            Description: Monoclonal...

Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs

May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry.

 

Biotin:

§  116, 142 – Monoclonal antibody to Biotin

           Description: Monoclonal antibodies raised against biotinylated BSA.

           Available clones: F1, F4.

Biotin, also known as vitamin H or coenzyme R, is a water-soluble B-vitamin (vitamin B7). Functions as coenzyme for carboxylase enzymes, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis.

Reference: Bag?i H1, Kohen F, Kus?uoglu U, Bayer EA, Wilchek M. 1993. Monoclonal anti-biotin antibodies simulate avidin in the recognition of biotin. FEBS Lett. 322(1):47-50.

 

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  • Dr. Fortune Kohen
117
Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry. Leukotrienes:   Drugs: §  117 – Monoclonal antibody to Digoxin         Description: Rat...

Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs

May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry.

Leukotrienes:

 

Drugs:

§  117 – Monoclonal antibody to Digoxin

        Description: Rat monoclonal antibodies raised against Digoxin.

        Available clone: 10F10, IgG1.

Digoxin is a purified cardiac glycoside similar to Digitoxin extracted from the foxglove plant, Digitalis lanata. Digoxin is widely used in the treatment of various heart conditions.

 
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  • Dr. Fortune Kohen
118
  Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry. Leukotrienes:   Drugs: §  118 - Monoclonal antibody to Buserelin      Description: Rat...

 

Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs

May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry.

Leukotrienes:

 

Drugs:

§  118 - Monoclonal antibody to Buserelin

     Description: Rat monoclonal antibodies raised against Buserelin.

     Available clone: 8B4, IgG1.

 
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  • Dr. Fortune Kohen
119
Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food products. Rat monoclonal antibodies raised against testosterone 3-(0- carboxymethyl)oxime-BSA. Available...

Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food products.
Rat monoclonal antibodies raised against testosterone 3-(0- carboxymethyl)oxime-BSA. Available clones: 5F2, 5A4.
Testosterone is the principal male sex hormone and an anabolic steroid. In mammals, testosterone is secreted primarily in the testicles of males and the ovaries of females, although small amounts are also secreted by the adrenal glands.
Reference: Kohen F, Lichter S, Eshhar Z, Lindner HR. 1982. Preparation of monoclonal antibodies able to discriminate between testosterone and 5 alpha-dihydrotestosterone. Steroids. 39(4):453-9.

Monoclonal antibodies for peptide and steroid hormones

Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food products.

Steroid Hormones:

§  119, 169 – Monoclonal antibodies to Testosterone          

      Description: Rat monoclonal antibodies raised against testosterone 3-(0-   carboxymethyl)oxime-BSA. Available clones: 5F2, 5A4.

Testosterone is the principal male sex hormone and an anabolic steroid. In mammals, testosterone is secreted primarily in the testicles of males and the ovaries of females, although small amounts are also secreted by the adrenal glands.

Reference: Kohen F, Lichter S, Eshhar Z, Lindner HR. 1982. Preparation of monoclonal antibodies able to discriminate between testosterone and 5 alpha-dihydrotestosterone. Steroids. 39(4):453-9.


 

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  • Dr. Fortune Kohen
120
Monoclonal antibodies raised against bFSH. Available clone: 1G12. Follicle-stimulating hormone (FSH) is synthesized and secreted by gonadotrophs of the anterior pituitary gland. FSH regulates the development, growth, pubertal maturation and reproductive processes of the body.Reference: Somjen D1,...

Monoclonal antibodies raised against bFSH. Available clone: 1G12.
Follicle-stimulating hormone (FSH) is synthesized and secreted by gonadotrophs of the anterior pituitary gland. FSH regulates the development, growth, pubertal maturation and reproductive processes of the body.
Reference: Somjen D1, Tordjman K, Kohen F, Baz M, Razon N, Ouaknine G, Stern N. 1997. Combined beta FSH and beta LH response to TRH in patients with clinically non-functioning pituitary adenomas. Clin Endocrinol (Oxf). 46(5):555-62.

Monoclonal antibodies for peptide and steroid hormones

Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food products.

 

Peptide Hormones:

§  120 – Monoclonal antibody to FSH

Description: Monoclonal antibodies raised against bFSH. Available clone: 1G12.

Follicle-stimulating hormone (FSH) is synthesized and secreted by gonadotrophs of the anterior pituitary gland. FSH regulates the development, growth, pubertal maturation and reproductive processes of the body.

      Reference: Somjen D1, Tordjman K, Kohen F, Baz M, Razon N, Ouaknine G, Stern N. 1997. Combined beta FSH and beta LH response to TRH in patients with clinically non-functioning pituitary adenomas. Clin Endocrinol (Oxf). 46(5):555-62.


 

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  • Dr. Fortune Kohen
127
Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food products. Monoclonal antibodies raised against oestradiol-6- carboxymethyl oxime-BSA. Available clones:...

Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food products.
Monoclonal antibodies raised against oestradiol-6- carboxymethyl oxime-BSA. Available clones: 2F9 (Rat, IgG2a), 15 (IgG2b),  8D9 (IgG2a).
Estradiol is a sex hormone, which has not only a critical impact on reproductive and sexual functioning, but also affects other organs, including the bones. In the female, estradiol acts as a growth hormone for tissues of the reproductive organs.
References: De Boever J, Kohen F, Usanachitt C, Vandekerckhove D, Leyseele D, Vandewalle L. 1986. Direct chemiluminescence immunoassay for estradiol in serum. Clin Chem. 32(10):1895-900.
S?mjen D1, Amir-Zaltsman Y, Mor G, Gayer B, Lichter S, Nevo N, Kohen F. 1998. A monoclonal antibody to oestradiol potentiates the stimulation of the specific activity of the brain type creatine kinase by oestrogen in vivo and in vitro. J Steroid Biochem Mol Biol. 64(5-6):297-304. 

Monoclonal antibodies for peptide and steroid hormones

Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food products.

 

§  127, 274, 141 – Monoclonal antibodies to estradiol         

      Description: Monoclonal antibodies raised against oestradiol-6-     carboxymethyl oxime-BSA. Available clones: 2F9 (Rat, IgG2a), 15 (IgG2b),    8D9 (IgG2a).

Estradiol is a sex hormone, which has not only a critical impact on reproductive and sexual functioning, but also affects other organs, including the bones. In the female, estradiol acts as a growth hormone for tissues of the reproductive organs.

            References: De Boever J, Kohen F, Usanachitt C, Vandekerckhove D, Leyseele D, Vandewalle L. 1986. Direct chemiluminescence immunoassay for estradiol in serum. Clin Chem. 32(10):1895-900.

            S?mjen D1, Amir-Zaltsman Y, Mor G, Gayer B, Lichter S, Nevo N, Kohen F. 1998. A monoclonal antibody to oestradiol potentiates the stimulation of the specific activity of the brain type creatine kinase by oestrogen in vivo and in vitro. J Steroid Biochem Mol Biol. 64(5-6):297-304.


 

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  • Dr. Fortune Kohen
130
Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry. Leukotrienes:   Veterinary drugs: §  130 - Anti-idiotypic antibody against anti-Sulfamethazine...

Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs

May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry.

Leukotrienes:

 

Veterinary drugs:

§  130 - Anti-idiotypic antibody against anti-Sulfamethazine

                              Description: Betetypic anti-idiotypic antibody raised against anti Sulfamethazine –KLH (clone 21C7). Available clone: 12E12.

Reference: Fortune Kohen , Batya Gayer , Yehudith Amir-Zaltsman &

Michael O'Keeffe. 2000. Generation of an anti-idiotypic antibody as a surrogateLigand for sulfamethazine in immunoassay procedures, food and agricultural. Immunology 12:3 193-201.

 
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  • Dr. Fortune Kohen
132
WISH-PC frozen tissue samples Description: Neuroendocrine xenograft model of human prostatic small cell carcinoma cancer. Provides a source to study the involvement of neuroendocrine cells in the progression of prostatic adenocarcinoma and can serve as a novel model for the testing of new therapeutic...

WISH-PC frozen tissue samples

Description: Neuroendocrine xenograft model of human prostatic small cell carcinoma cancer. Provides a source to study the involvement of neuroendocrine cells in the progression of prostatic adenocarcinoma and can serve as a novel model for the testing of new therapeutic strategies for prostatic small cell carcinoma.

WISH-PC2: Taken from a patient diagnosed with T3N1M1 prostatic adenocarcinoma with a Gleason score of 8 (3 + 5). Obtained during a palliative transuretheral resection of the prostate. Independent of Androgen and does not secretes prostate-specific antigen.

WISH-PC14: Taken from a channel transurethral resection of the prostate of a late recurrent primary tumor, Gleason score 9 (4 + 5), after definitive radiation therapy. Androgen dependent and secretes prostate-specific antigen.

WISH-PC23: Taken from prostatic adenocarcinoma harvested during palliative trans urethral resection of the prostate performed in a patient with local progression of adenocarcinoma of the prostate, Gleason score 6 (3 + 3).

Reference: Pinthus JH, Waks T, Schindler DG, Harmelin A, Said JW, Belldegrun A, Ramon J, Eshhar Z. 2000. WISH-PC2: a unique xenograft model of human prostatic small cell carcinoma. Cancer Res. 60(23):6563-7.

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  • Prof. Zelig Eshhar
138
Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food products. Monoclonal antibodies raised against progesterone-7- carboxythio thioether-BSA (clone 2H4, Rat...

Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food products.
Monoclonal antibodies raised against progesterone-7- carboxythio thioether-BSA (clone 2H4, Rat IgG1) and progesterone-11- hemisuccinate-BSA (clone 1E11, IgG1).
Progesterone is a C-21 steroid hormone involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species.
Reference: Jozef G. De Boever, Fotune Kohen, Eugene Bosmans. 1994.  Binding of homologous and heterologous isoluminol- and enzyme-labelled  progesterone conjugates to monoclonal antibodies. Analytica Chimica Acta.  290: 239-245

 

Monoclonal antibodies for peptide and steroid hormones

Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food products.

 

§  138,146 – Monoclonal antibodies to Progesterone          

      Description:  Monoclonal antibodies raised against progesterone-7- carboxythio thioether-BSA (clone 2H4, Rat IgG1) and progesterone-11- hemisuccinate-BSA (clone 1E11, IgG1).

Progesterone is a C-21 steroid hormone involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species.

      Reference: Jozef G. De Boever, Fotune Kohen, Eugene Bosmans. 1994.      Binding of homologous and heterologous isoluminol- and enzyme-labelled   progesterone conjugates to monoclonal antibodies. Analytica Chimica Acta.    290: 239-245


 

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  • Dr. Fortune Kohen
141
Monoclonal antibodies for peptide and steroid hormones Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food products.   §  127, 274, 141 – Monoclonal...

Monoclonal antibodies for peptide and steroid hormones

Due to their high specificity and sensitivity these antibodies may be applicable for research, diagnosis and therapeutics. A particular use may be quality control of industrial manufacturing of food products.

 

§  127, 274, 141 – Monoclonal antibodies to estradiol         

      Description: Monoclonal antibodies raised against oestradiol-6-     carboxymethyl oxime-BSA. Available clones: 2F9 (Rat, IgG2a), 15 (IgG2b),    8D9 (IgG2a).

Estradiol is a sex hormone, which has not only a critical impact on reproductive and sexual functioning, but also affects other organs, including the bones. In the female, estradiol acts as a growth hormone for tissues of the reproductive organs.

            References: De Boever J, Kohen F, Usanachitt C, Vandekerckhove D, Leyseele D, Vandewalle L. 1986. Direct chemiluminescence immunoassay for estradiol in serum. Clin Chem. 32(10):1895-900.

            S?mjen D1, Amir-Zaltsman Y, Mor G, Gayer B, Lichter S, Nevo N, Kohen F. 1998. A monoclonal antibody to oestradiol potentiates the stimulation of the specific activity of the brain type creatine kinase by oestrogen in vivo and in vitro. J Steroid Biochem Mol Biol. 64(5-6):297-304.

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  • Dr. Fortune Kohen
142
Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry.   Biotin: §  116, 142 – Monoclonal antibody to Biotin            Description: Monoclonal...

Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs

May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry.

 

Biotin:

§  116, 142 – Monoclonal antibody to Biotin

           Description: Monoclonal antibodies raised against biotinylated BSA.

           Available clones: F1, F4.

Biotin, also known as vitamin H or coenzyme R, is a water-soluble B-vitamin (vitamin B7). Functions as coenzyme for carboxylase enzymes, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis.

Reference: Bag?i H1, Kohen F, Kus?uoglu U, Bayer EA, Wilchek M. 1993. Monoclonal anti-biotin antibodies simulate avidin in the recognition of biotin. FEBS Lett. 322(1):47-50.

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  • Dr. Fortune Kohen
143
Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry. Leukotrienes: Drugs: §  143 - Monoclonal antibody to Medroxy-progesterone-acetate     ...

Monoclonal antibodies for Isoflavones, leukotrienes, biotin and human and veterinary drugs

May be used for monitoring drug additives in food providing animals for veterinary use and for the food industry.

Leukotrienes:

Drugs:

§  143 - Monoclonal antibody to Medroxy-progesterone-acetate

     Description: Rat monoclonal antibodies raised against Medroxy-progesterone- acetate(MPA)-3-carboxymethyl oxime- BSA. Available clone: 1F5, IgG1.

     Medroxy-progesterone-acetate (MPA) is a highly potent progestational steroid that has been used worldwide as a contraceptive.

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  • Dr. Fortune Kohen

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